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23 AUG 21 :: New SARS-CoV-2 variants have changed the pandemic. What will the virus do next? @ScienceMagazine @kakape |
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23 AUG 21 :: "When I first saw the furin cleavage site in the viral sequence... I said to my wife it was the smoking gun... mak[ing] a powerful challenge to the idea of a natural origin for #SARSCoV2." virologist David Baltimore, former president of @Caltech |
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23 JUL 21 :: If original SARS2's furin cleavage site would have been as efficient, its R0 would have been around 6, which means by now we would have probably had ~40M dead and ~1B infected. @ydeigin |
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23 JUL 21 :: 27-JUL-2020 It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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23 JUL 21 :: Humanity is extremely lucky that Delta's single nucleotide mutation in the furin cleavage site which has overclocked SARS2's transmissibility by an order of magnitude only got traction in May 2021, rather than May 2020. @ydeigin |
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22 JUL 21 :: Humanity is extremely lucky that Delta's single nucleotide mutation in the furin cleavage site which has overclocked SARS2's transmissibility by an order of magnitude only got traction in May 2021, rather than May 2020. @ydeigin |
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22 JUL 21 :: If original SARS2's furin cleavage site would have been as efficient, its R0 would have been around 6, which means by now we would have probably had ~40M dead and ~1B infected. @ydeigin |
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6 JUL 21 :: It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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5 JUL 21 :: It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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24 JUN 21 :: 27-JUL-2020 It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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18 JUN 21 :: 27-JUL-2020 It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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15 JUN 21 :: The Battle Over the Coronavirus Lab-Leak Theory @NewYorker H/T @gdemaneuf |
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15 JUN 21 :: 27-JUL-2020 It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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9 JUN 21 :: The murky origins of the coronavirus SARS-CoV-2, the causative agent of the COVID-19 pandemic P. Balaram National Centre for Biological Sciences, Bengaluru |
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9 JUN 21 :: 27-JUL-2020 It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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3 JUN 21 :: 27-JUL-2020 :: It is impossible to ignore the introduction of a PRRA insert between S1 and S2: it sticks out like a splinter. This insert creates the furin cleavage site |
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3 JUN 21 :: Is Kristian talking about the furin cleavage site insertion? @ydeigin |
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31 MAY 21 :: The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade |
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12 MAY 21 :: An even more polybasic furin cleavage site in SARS2 cannot be a good thing. RRRAR in the mutant instead of the canonical PRRAR. Could it be the reason behind the third wave spikes in India and other countries? @@ydeigin |
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12 MAY 21 :: The Indian SARS2 strain with the more polybasic furin site (RRRAR instead of PRRAR) is spreading fast in UK now. @ydeigin |
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